A key finding in our study has been a strong trend toward altered lipid metabolism between SD and WKY rats, which may, at least in part, explain differences in behaviour between the two rat strains.
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Metabolome and microbiome profiling of a stress-sensitive rat model of gut-brain axis dysfunction.
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The sentences
Of the glycosphingolipids (CerG1) that were annotated, one trended toward an increase in response to stress while two showed a decreasing trend.
WKY rats had 49 different brain lipid species between non-stressed (control) and stressed groups that reached close to significance following FDR correction.