All-cause mortality and survival in adults with 22q11.2 deletion syndrome.

Results for intellectual disability 14 had a small independent effect on mortality though did not reach statistical significance.

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Risk factors for all-cause mortality in 22q11.2DS Consistent with our hypothesis, the Cox proportional hazards model for all-cause mortality comparing 22q11.2DS with unaffected siblings was highly significant (Table 2 ).

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There was a nonsignificant trend for longer survival in the more recently ascertained subgroup of 209 individuals compared with those ascertained 10 or more years ago (log rank χ 2 = 3.47, df = 1, p = 0.0623) (ref. 5 ).

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