The distribution of interleukin-6 (IL-6) mRNA levels trended higher in CPB/DHCA animals but this difference did not reach statistical significance (4.7 (range 0.27–15.44 vs 1 (range 0.15–9.65); p = 0.16) (Supplemental Figure S5 ).
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Alkaline Phosphatase Treatment of Acute Kidney Injury in an Infant Piglet Model of Cardiopulmonary Bypass with Deep Hypothermic Circulatory Arrest.
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The sentences
There was a nonsignificant trend towards differential distribution of NGAL mRNA by severity of AKI (mild-to-moderate injury: median 2.1-fold increase (range 1–27.6); severe injury 1.4-fold increase (range 0.7–6.2); no injury 1.4-fold increase (range 0.8–8.2); p = 0.13 for a difference among groups) (Supplemental Figure S8 ).