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Comprehensive biomarker analyses identifies <i>HER2, EGFR, MET</i> RNA expression and thymidylate synthase 5'UTR SNP as predictors of benefit from S-1 adjuvant chemotherapy in Japanese patients with stage II/III gastric cancer.

J Cancer · 2019 · PMC6775596 · PMID 31602266

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Patients with TS 5'UTR 2R/3G or 3C/3G or 3G/3G tended to have poorer survival than those with 2R/2R, 2R/3C, or 3C/3C (HR =2.185, p=0.058) but the difference did not reach statistical significance.

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