Gingival solitary chemosensory cells are immune sentinels for periodontitis.

Although differences in the Shannon indices did not reach statistical significance, the α diversity of the oral microbiome from Gnat3 −/− mice were reduced compared to those of WT (see Supplementary Fig. 6E ).

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The enrichment of Pasteurella may be significant: a pathogen (NI1060) belonging to this genus has been associated with ligature-induced periodontitis 15 .

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