Quantification of the CD11b staining showed a clear trend towards increased presence of leukocytes in the dystrophic muscle at day 4 and 7, and a significant difference between wild-type and age-matched dy 3K /dy 3K muscle at day 14 and 21 (Fig. 6b ).
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Early skeletal muscle pathology and disease progress in the dy<sup>3K</sup>/dy<sup>3K</sup> mouse model of congenital muscular dystrophy with laminin α2 chain-deficiency.
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This difference became highly significant at day 21 (Fig. 4c ).