Barely Significant
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Impact of Tenofovir-Based Pre-exposure Prophylaxis on Biomarkers of Bone Formation, Bone Resorption, and Bone Mineral Metabolism in HIV-Negative Adults.

Open Forum Infect Dis · 2019 · PMC6778426 · PMID 31660332

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Although the proportion of participants who experienced a clinically significant decline in eGFR of ≥25% from baseline was higher among participants randomized to active PrEP, this difference did not reach statistical significance.

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