Impact of the Dual Deletion of the Mitochondrial Sirtuins SIRT3 and SIRT5 on Anti-microbial Host Defenses.

Front Immunol · 2019 · PMC6781768 · PMID 31632409

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Going well along with an increased inflammatory response of BMDMs ( Figure 3 ), SIRT3/5 −/− whole blood produced more G-CSF and showed a trend toward producing more IL-1α, IL-6, and IFNγ than SIRT3/5 +/+ whole blood ( Figure 4F ).

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