Why Be One Protein When You Can Affect Many? The Multiple Roles of YB-1 in Lung Cancer and Mesothelioma.

Front Cell Dev Biol · 2019 · PMC6781797 · PMID 31632972

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YB-1 is overexpressed in mesothelioma compared to non-malignant mesothelial cells in vitro ( Johnson et al., 2018 ) and a small study of 33 MPM patients showed a trend toward higher YB-1 expression in sarcomatoid MPM tumors, which are associated with shorter survival ( Iwanami et al., 2014 ).

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