Inflammatory markers in intrahepatic cholangiocarcinoma: Effects of advanced liver disease.

Higher survival was also seen in resection (n = 28; low‐ vs high‐NLR; median OS 36.4 vs 42.4 months; P = 0.83) and IO (n = 16; low‐ vs high‐NLR; median OS 33.1 vs 10.7 months; P = 0.0674), although this did not reach statistical significance. 3.7 Liver status and NLR Patients with Child‐Pugh A disease had higher median ALC ( P < 0.05), whereas patients with Child‐Pugh B/C disease had higher comorbidity indices (median 10.0 vs 6.5, P < 0.0001), MELD scores (13.0 vs 7.0, P < 0.0001), and higher rates of cirrhosis ( P < 0.05).

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While this survival difference was also seen on subgroup analyses in patients with Child‐Pugh A disease, it became a nonsignificant trend among patients with Child‐Pugh B disease.

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