approaching significancep = 0.06
Notably, scores for this subgroup were higher overall in the HOT compared to the CONTROL trial (main effect for trial approaching significance; p = 0.06), with moderate to large ES found between trials at baseline, 60, 90 and 120 min ( d = 0.83 [-0.17, 1.75] to 1.81 [0.64, 2.81]).