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Prognostic significance of peripheral CD8+CD28+ and CD8+CD28- T cells in advanced non-small cell lung cancer patients treated with chemo(radio)therapy.

J Transl Med · 2019 · PMC6796409 · PMID 31623615

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However, we found that the prognostic value of CD8+CD28+ T cells in SCCs and CD8+CD28− T cells in ADs did not reach statistical significance, which may have arisen from the differences in tumor immunity, gene expression, and methylation between ADs and SCCs [ 6 , 17 – 20 ].

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