In a set of 2-week-old LTCFDN mice (regardless of their genders), we observed that hepatic TG content was increased ( Fig 1A ) while their hepatic free fatty acid (FFA) level showed a trend of increase ( Fig 1B ).
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The developmental Wnt signaling pathway effector β-catenin/TCF mediates hepatic functions of the sex hormone estradiol in regulating lipid metabolism.
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