Elevated perceived threat is associated with reduced hippocampal volume in combat veterans.

In addition, regressing hippocampal volume on perceived threat while simultaneously controlling for correlated self-report measures of anxiety, depression, and worry scores showed a trend-level relationship for perceived threat ( t (33) = −1.87, b = −32.4, p = 0.071) and no relationships for any of the other self-report indices (all | t s| < 0.8, all | b s| < 17, all p s > 0.4).

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