Again, although we observed a tendency to lower expression levels of the different shelterin components in hyper-long telomere mice compared to the controls both in the liver, this difference did not reach statistical significance (Supplementary Fig. 2e–k ), similar findings were observed and in the white adipose tissue (Supplementary Fig. 2l–r ).
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Mice with hyper-long telomeres show less metabolic aging and longer lifespans.
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