Unmet Needs in Pharmacological Treatment of Apathy in Alzheimer's Disease: A Systematic Review.

Front Pharmacol · 2019 · PMC6797825 · PMID 31680942

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slightly significantno p-value reported

On the other hand, discontinuation of AChEIs (1 study) revealed no significant improvement, antipsychotics (two studies) worsened apathy, discontinuation of antipsychotics (one study) revealed a slightly significant improvement, while there was uncertainty for what concerns antidepressants (two studies) due to very low evidence quality.

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