Three Novel Loci for Infant Head Circumference Identified by a Joint Association Analysis.

Front Genet · 2019 · PMC6798153 · PMID 31681408

Europe PMC DOI

hedged sentences

0.0200

closest p · 0.4× alpha

0.0200

boldest claim

The sentences

nominally significantp = 0.02actually significant

We could not replicate rs3795128 (20q12) in intracranial volume at Bonferroni-corrected threshold, although it was nominally significant (one-sided p = 0.02) in this dataset.

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extremely significantno p-value reported

Of the nine lead SNPs, four are not significant in the original HC study at the nominal level (α = 0.05) but extremely significant for BW and BL, indicating that the significant signals are likely to be driven solely by BL and/or BW instead by HC.

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