DNA methylation-based biological age, genome-wide average DNA methylation, and conventional breast cancer risk factors.

As to the Levine clock, the association for obese women was marginally significant: β = 1.29, 95% CI = −0.01 to 2.58, P = 0.05.

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The associations for the Hannum clock were not statistically significant from any of the meta-analyses, and the rest of the associations were found to be nominally significant in at least one of the meta-analyses, with the exception that the association between number of live births and genome-wide average DNA methylation was marginally significant ( P = 0.07).

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