Role of Regulatory T Cell and Effector T Cell Exhaustion in Liver-Mediated Transgene Tolerance in Muscle.

Mol Ther Methods Clin Dev · 2019 · PMC6804827 · PMID 31649958

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did not reach statistical significanceno p-value reported

Animals receiving vectors both in muscle and in liver and treated with the combination of anti-PD-1, anti-PDL-1, and anti-LAG3 antibodies (Muscle-Liver+Ab) showed increased anti-hSGCA humoral immune response compared with the Muscle-Liver group, although the difference did not reach statistical significance.

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