Coffee intake and decreased amyloid pathology in human brain.

1 , there was a significant trend of association between lifetime coffee intake strata and Aβ positivity ( p = 0.048).

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Multiple logistic regression analysis also demonstrated that there was a trend toward significance on dose–effect association between the total amount of lifetime coffee intake (=duration of coffee intake × cups of coffee intake/day) and Aβ positivity [OR (95% CI) = 0.991 (0.982–1.001), p = 0.067].

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