The non-coding RNome after splenectomy.

38 , 39 By using RT‐qPCR, we observed that miR‐324 is statistically overexpressed post‐splenectomy in peripheral blood leucocytes ( P = .0455) and miR‐335 fallowed the same trend like in the array profiling but did not reach statistical significance because of the heterogeneous expression among the patients (Figure 2 J). 3.3 Deregulated miRNAs and T‐PYKs are part of a complex transcriptional network To obtain further insights into the mechanism of the deregulated ncRNA transcripts we analysed the downstream pathways controlled by differently expressed cellular miRNAs and checked the expression correlations between deregulated miRNAs and T‐PYKs.

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