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Ultrasound and Microbubble-targeted Delivery of a microRNA Inhibitor to the Heart Suppresses Cardiac Hypertrophy and Preserves Cardiac Function.

Theranostics · 2019 · PMC6815962 · PMID 31660088

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Cardiac levels of hypertrophy markers ANP and MYH7 mRNA were less at 2 weeks in phenylephrine-treated mice receiving UTMC + antimiR-23a microbubble treatments compared to treatment with UTMC + antimiR-NC microbubbles (Online Figure S5 ) although the differences did not reach statistical significance.

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