A review of complement sources used in serum bactericidal assays for evaluating immune responses to meningococcal ACWY conjugate vaccines.

Hum Vaccin Immunother · 2019 · PMC6816443 · PMID 30883271

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a clear trendno p-value reported

In general, hSBA assay results presented in MenACWY-TT studies do not show a clear trend across serogroups. 60 , 62 , 65 , 67 – 69 , 74 , 76 , 78 Correlation of observed protection with serology Postlicensure studies of vaccine effectiveness have served as critical sources for validation and refinement of the use of SBA assays.

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