Sustained activity of novel THIOMAB antibody-antibiotic conjugate against Staphylococcus aureus in a mouse model: Longitudinal pharmacodynamic assessment by bioluminescence imaging.

PLoS One · 2019 · PMC6818770 · PMID 31661493

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showed a trendno p-value reported

Compared to TAC monotherapy at the same dose level, combination treatment of 50 mg/kg TAC and vancomycin showed a trend of lower total luminescence intensity (2.96 ×10 8 vs . 3.95×10 8 p), although the difference was not statistically significant ( S5 Fig ).

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