a strong trendP = 0.054
However, like Myc high -only tumors, and quite unlike Myc low -only tumors, Myc high /Myc low chimeric tumors were invasive, angiogenic, and predominantly normoxic, exhibiting little necrosis and displaying a strong trend toward increased cellularity ( P = 0.054) ( Fig. 2 C – F and SI Appendix , Fig.