The tumor inflammation signature (TIS) is associated with anti-PD-1 treatment benefit in the CERTIM pan-cancer cohort.

J Transl Med · 2019 · PMC6829827 · PMID 31684954

Europe PMC DOI

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The sentences

did not reach statistical significancep = 0.13not close (p > 0.1)

PD-L1 staining ≥ 1% tumor cells was not significantly associated with survival (hazard ratio = 0.87, CI [0.4, 2], p = 0.74), and PD-L1 staining on 50% tumor cells had a trend with overall survival but did not reach statistical significance (hazard ratio = 0.40, CI [0.1, 1.3], p = 0.13) (Fig. 2 c, d).

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