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Antibiotic stewardship in skin infections: a cross-sectional analysis of early-career GP's management of impetigo.

BMJ Open · 2019 · PMC6830714 · PMID 31662391

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showed a trendno p-value reported
6 This 2001 study also showed a trend of increasing topical antibiotic use compared with 1987 data which had found 43% topical, 31% oral and 11% antiseptic use.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.