A 3' UTR SNP rs885863, a cis-eQTL for the circadian gene VIPR2 and lincRNA 689, is associated with opioid addiction.

PLoS One · 2019 · PMC6830932 · PMID 31689297

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0.0100

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nominally significantp < 0.01actually significant

Nominally significant associations ( p < 0.01) were detected for several variants in genes encoding vasoactive intestinal peptide receptor 2 ( VIPR2 ), period circadian regulator 2 ( PER2 ), casein kinase 1 epsilon ( CSNK1E ), and activator of transcription and developmental regulator ( AUTS2 ), but no signal survived correction for multiple testing.

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