Beneficial effects of PGC-1α in the substantia nigra of a mouse model of MPTP-induced dopaminergic neurotoxicity.

Aging (Albany NY) · 2019 · PMC6834419 · PMID 31634150

Europe PMC DOI

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a decreasing trendno p-value reported

an increasing trendno p-value reported

Electron microscopy showed an increasing trend in the mitochondrial density in the LVPGC+M group and a decreasing trend in the M and LVsiRNA+M groups compared to that in the controls.

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did not reach statistical significanceno p-value reported

However, these trends did not reach statistical significance, possibly due to the small sample size and individual diversity within experimental animals.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.