Study of Fecal and Urinary Metabolite Perturbations Induced by Chronic Ethanol Treatment in Mice by UHPLC-MS/MS Targeted Profiling.

Metabolites · 2019 · PMC6836053 · PMID 31623107

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an increasing trendno p-value reported

For some metabolites (e.g., amino acids), an increasing trend was observed, while for others (e.g., amines), a decrease was observed in the earlier time point followed by an increase in the second time point.

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an adverse trendno p-value reported

From the altered metabolites in the second time point, 15 were already altered in the first time point, while L-acetylcarnitine, putrescine and tryptamine demonstrated an adverse trend between the two time points.

also in 93 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.