Blockade of IL-27 signaling ameliorates herpes stromal keratitis with upregulated CD4⁺ Foxp3⁺ regulatory T cells influx in mice.

Although the mean viral titers in tear film of anti-IL-27-treated mice were lower than those of IgG-treated mice at any time points monitored, the difference did not reach statistical significance [ Fig. 5 ].

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