Effects of renal denervation on kidney function and long-term outcomes: 3-year follow-up from the Global SYMPLICITY Registry.

69 ± 25 mL/min/1.73 m 2 , P = 0.41). The 6-month change in eGFR was numerically higher but did not reach statistical significance in patients with diabetes mellitus compared with those without diabetes mellitus [−4.1 ± 12.6 mL/min/1.73 m 2 ( n = 157) vs. −2.6 ± 13.4 mL/min/1.73 m 2 ( n = 224), P = 0.090] and likewise no significant difference was observed at 3 years [−7.7 ± 18.1 mL/min/1.73 m 2 ( n = 157) vs. −5.2 ± 15.5 mL/min/1.73 m 2 ( n = 224), P = 0.053].

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