showed a trendp = .007
Patients with MAPT mutations showed a trend towards more severe atrophy in left entorhinal cortex (U = 2.0, z = −2.68, p = .007) and fusiform gyrus (U = 1.5, z = −2.72, p = .006) and right perirhinal cortex (U = 1.5, z = −2.67, p = .007) than patients with mutations in the GRN and C9orf72 gene and in right fusiform gyrus compared to bvFTD patients with no gene mutation (U = 13.0, z = −2.80, p = .005). 4 Discussion In this large cohort of bvFTD patients naming problems were a prominent feature of many, although not all, patients (around 50%).