It is noteworthy that a trend approaching significance ( p < 0.1) was observed in the tau T175D expressing group for increased motor neuron TDP-43 pathology (Fig. 3 a).
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Synergistic toxicity in an in vivo model of neurodegeneration through the co-expression of human TDP-43<sup>M337V</sup> and tau<sup>T175D</sup> protein.
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