did not reach statistical significancep = 0.0679
While the repeated measures correlation coefficient was low ( r = 0.617) and did not reach statistical significance ( p = 0.0679, q = 0.199, dof = 14), the daily average intensity value for quinic acid, another known metabolite from coffee, 36 tracked much more quantitatively with coffee consumption (Supplementary Fig. 3 ; r = 0.787, p = 2.93e−4, q = 0.0877, dof = 14).