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HCN4 knockdown in dorsal hippocampus promotes anxiety-like behavior in mice.

Genes Brain Behav · 2019 · PMC6850037 · PMID 30585408

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However, rAAV‐shHcn4‐treated mice reliably showed slightly higher freezing levels than control‐treated littermates during the 24‐hour test as well as lower freezing levels during extinction, although this result did not reach statistical significance (Figure S9).

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