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Transepidermal UV radiation of scalp skin ex vivo induces hair follicle damage that is alleviated by the topical treatment with caffeine.

Int J Cosmet Sci · 2019 · PMC6850087 · PMID 30746733

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showed a trendno p-value reported
Caffeine treatment alone significantly up‐regulated IGF‐1 expression, although skin exposure to the combination of 40 J/cm 2 UVA and 40 mJ/cm 2 UVB showed a trend towards increase expression of both IGF‐1 and TGF‐ β 2 expression in the proximal HF ORS (Figure 10 a–c).

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