16 Employment of mild HA patients was 60% (27/45) compared to 68% (21/31) for healthy controls in a Canadian cohort; the difference did not reach statistical significance. 26 In a multicentre US study, mild HA patients missed an average of 6.2 work days per year, of which 4.7 days (76%) were due to HA. 3 Finally, a retrospective study in Italy noted 3.4 missed days of work per year, with no benchmark provided for patients without HA. 23 Table 4 summarizes the data available for health care cost and utilization and societal impacts (direct and indirect costs of mild HA). 3.8.
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