SNP eQTL status and eQTL density in the adjacent region of the SNP are associated with its statistical significance in GWA studies.

BMC Genet · 2019 · PMC6852916 · PMID 31718536

Europe PMC DOI

hedged sentences

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closest p · 0.0× alpha

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boldest claim

The sentences

quasi-significantp < 5 × 10 − 8actually significant

The observed associations suggest that quasi-significant SNPs (10 − 5 < p < 5 × 10 − 8 ) and SNPs at the genome wide level of statistical significance ( p < 5 × 10 − 8 ) may have a similar proportions of risk associated SNPs.

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nominally significantno p-value reported

Those features could be used to select SNPs from gray zones (SNPs that are nominally significant but do not reach the genome-wide level of significance) for targeted analyses.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.