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Focal epilepsy caused by single cerebral cavernous malformation (CCM) is associated with regional and global resting state functional connectivity (FC) disruption.

Neuroimage Clin · 2019 · PMC6854067 · PMID 31734529

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Even though these changes did not reach statistical significance in our analyses, they raised the possibility of using these values to delineate the epileptogenic zone (EZ) and, hence, to guide the surgical resection.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.