Interestingly, these observations were not in line with a similar regulation of circulating miR-143 in our large collective of ICU patients, since miR-143 showed only a nonsignificant trend towards lower levels in critically ill patients compared to controls.
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The sentences
Results In the total cohort of critically ill patients from a medical intensive care unit (ICU), miR-143 serum levels tended to be lower compared to healthy control samples, but this difference did not reach statistical significance.