Copenhagen Head Injury Ciclosporin Study: A Phase IIa Safety, Pharmacokinetics, and Biomarker Study of Ciclosporin in Severe Traumatic Brain Injury Patients.

J Neurotrauma · 2019 · PMC6857463 · PMID 31210099

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showed a trendno p-value reported

Two patients showed reductions (improvements) in lactate/pyruvate ratio after initiation of study treatment, and 4 patients showed a trend of increased lactate/pyruvate ratio after the termination of study treatment.

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