A regulatory variant of CHRM3 is associated with cannabis-induced hallucinations in European Americans.

Transl Psychiatry · 2019 · PMC6861240 · PMID 31740666

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nominally significantno p-value reported

In the meta-analysis of Yale-Penn EAs ( n = 1917), one genome-wide significant (GWS) signal emerged at the CHRM3 locus, represented by rs115455482 ( P = 1.66 × 10 −10 ), rs74722579 ( P = 2.81 × 10 −9 ), and rs1938228 ( P = 1.57 × 10 −8 ); signals were GWS in Yale-Penn 1 EAs ( n = 1092) and nominally significant in Yale-Penn 2 EAs ( n = 825).

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