showed a trendp = 0.081
Accordingly, the results of the open field test showed a trend toward decreased anxiety ( Figure 2B , young: p = 0.081, aged: p = 0.292) and anxiety was significantly reduced in the young MIM KO cohort in the light/dark test [young: F (1,42) = 14.20, p = 0.001, aged: p = 0.812].