Genetic Influences on Alcoholism Risk: A Review of Adoption and Twin Studies.

Once again, however, rates of alcoholism were significantly elevated in both MZ and DZ twins of alcoholics (i.e., risk ratios of 3.9 and 2.4, respectively), and evidence showed a higher risk to MZ than to DZ twins (although this result did not reach statistical significance). 6 Combining Results From Different Studies How can results across different studies or even within studies (e.g., between men and women) be compared?

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Romanov and colleagues (1991) conducted a further followup of a subsample of the same twin cohort using a broader definition of alcoholism that included alcohol abuse-related discharge codes (e.g., alcoholic liver cirrhosis and alcoholic psychosis) and found a nonsignificant trend in the same direction (i.e., risk ratios of 8.8 versus 4.6, respectively).

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