Genetic and clinical characterization of BRCA-associated hereditary breast and ovarian cancer in Navarra (Spain).

BMC Cancer · 2019 · PMC6880350 · PMID 31771539

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did not reach statistical significanceno p-value reported

The difference did not reach statistical significance when compared with the high risk BRCA -negative group (HR- BRCA -negative).

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a decreasing trendno p-value reported

This rate is comparable with other studies [ 14 , 18 , 19 ] and similarly shows a decreasing trend over time, moving from 30% in 2000–2005, to 17% during (2006–2010) and 14% from 2011 to 2016.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.