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Altered profiles of fecal metabolites correlate with visceral hypersensitivity and may contribute to symptom severity of diarrhea-predominant irritable bowel syndrome.

World J Gastroenterol · 2019 · PMC6881512 · PMID 31798278

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The level of isobutyrate was higher in the IBS-D group than in the controls, but the difference did not reach statistical significance.

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