A high-throughput screen identifies that CDK7 activates glucose consumption in lung cancer cells.

Nat Commun · 2019 · PMC6884612 · PMID 31784510

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did not reach statistical significanceno p-value reported

Overexpression of wild-type CDK7 in H460 cells also decreased the ability of Milciclib to block cell growth although this result did not reach statistical significance (normalized cell numbers of H460 cells transfected with control, wild-type CDK7, and T170A CDK7 and treated with Milciclib: 86.4 ± 9.0%, 101.1 ± 8.7%, and 81.5 ± 7.7%, respectively).

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