Barely Significant
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Using Botulinum Toxin A for Treatment of Interstitial Cystitis/Bladder Pain Syndrome-Possible Pathomechanisms and Practical Issues.

Toxins (Basel) · 2019 · PMC6891305 · PMID 31689912

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The sentences

an increasing trendno p-value reported
Although the prevalence has shown an increasing trend in recent years [ 4 ], the treatment of patients with IC/BPS remains challenging for urologists.

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Symptomatic improvement among injections did not reach statistical significance, particularly in terms of incontinence episodes and voided volume.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.