Oxidative Stress Attenuates TLR3 Responsiveness and Impairs Anti-viral Mechanisms in Bronchial Epithelial Cells From COPD and Asthma Patients.

Front Immunol · 2019 · PMC6895140 · PMID 31849956

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Similar to bronchial epithelial cells from asthmatics, pre-treatment with H 2 O 2 showed a trend toward dose-dependent reduction of poly(I:C)-induced expression of IFNβ in COPD bronchial epithelium ( Figure 5A ).

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